Phospho-sting ser366

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August undefined, 2024

Web(A) At 72 hours post-treatment protein was extracted for immunoblot analysis of phospho-TBK1 (Ser172), total TBK1, phospho-STING (Ser366 in human and Ser365 in murine) and total STING expression with vinculin as loading control. Numbers below the blots represent phosphorylated protein levels quantified by densitometric analysis. WebPhospho-STING (Ser366) one-plate assay protocol Detection of Phosphorylated STING (Ser366) with HTRF reagents can be performed in a single plate used for culturing, …

(85735) Phospho-STING (Ser366) Antibody - CiteAb

WebPhospho-STING (Ser366) Antibody (PA5-117276) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser366) Polyclonal Antibody ( Product # PA5-117276 … WebJul 7, 2024 · To initiate signaling, serine 365 (S365) in the C-terminal tail (CTT) of STING is phosphorylated, leading to induction of type I interferons (IFNs). Additionally, evolutionary … dan hayhurst bodyguard photos

(85735) Phospho-STING (Ser366) Antibody - CiteAb

WebPhospho-STING (Ser366) Antibody recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification … WebProduct NameSTING (Phospho-Ser366) Antibody Host SpeciesRabbit ClonalityPolyclonal PurificationThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. ApplicationsWB IHC IF ELISA Species ReactivityHu, Ms WebThis HTRF cell-based assay conveniently and accurately quantifies phosphorylated STING at Ser366. Following pathogen infection and binding of dsDNA to the cytoplasmic sensor … birr town

STING Ser366 phosphorylation by TBK1 recruits IRF3. (A) …

Phospho-STING (Ser366) cellular HTRF kit Cisbio - PerkinElmer

WebPhospho-STING (Ser366) Antibody detects endogenous levels of STING only when phosphorylated at Ser366 MyBioSource.com P.O. Box 153308 San Diego, California United States Phone: 1-888-627-0165 (toll free) or 1-858-633-0165 Fax: 1-858-633-0166 Email: [email protected] Company Profile Website: http://www.MyBioSource.com Webwithin the extracellular domain. Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor® 647 Conjugate) recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Source/Purification: Monoclonal antibodies were purified from tissue culture supernatant via affinity chromatography. dan hays attorney okcWebELISA Kits detecting STING can be used to research antiviral response and innate immune response against intracellular pathogen. or to study infectious diseases. STING, also known as Endoplasmic reticulum interferon stimulator (ERIS), is a symbol of Stimulator of interferon genes protein. Your search returned 17 STING ELISA Kit across 4 suppliers. birrung the secret friend pdf

"WebThe Human Monocyte STING Activation Flow Cytometry Panel includes antibodies targeting phospho-STING (Ser366) and phenotyping markers to enable observation of STING … " - Phospho-sting ser366

Phospho-sting ser366

WebFeb 19, 2024 · 3 novel HTRF STING assays have been developed to identify and characterize compounds targeting the STING protein. ... IRF3 and IFN-beta. Discover STING assays. PHOSPHO-STING (SER366) CELLULAR KIT. TOTAL STING CELLULAR KIT. HUMAN STING BINDING KIT. Get on the list to receive remarkable content. Subscribe. Life sciences; In … WebJun 17, 2024 · The cGAS-STING pathway operates as a first line of host immune defense against pathogens. cGAS, an innate immune sensor ( Sun et al., 2013 ), interacts with cytosolic nucleic acids including ssDNA ( Herzner et al., 2015 ), dsDNA ( Ishikawa and Barber, 2008 ), and DNA:RNA hybrids ( Guerra et al., 2024 ), producing the cyclic GMP …

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WebJun 3, 2024 · STING-GFP expression was similar in control and VPS13C KO cells ( Fig. S4 A ), and phospho-STING (Ser366) and phospho-TBK1 (Ser172) remained elevated in the VPS13C KO cells ( Fig. S4, B and C ). In WT cells, STING-GFP was almost exclusively localized to the ER, as expected ( Fig. 5, A and B ). WebPhospho-IRF-3 (Ser396) (D6O1M) Rabbit mAb (upper) or IRF-3 (D6I4C) XP® Rabbit mAb #11904 (lower). STING (D2P2F) Rabbit mAb #13647: IHC analysis of paraffin-embedded human colon carcinoma using STING (D2P2F) Rabbit mAb. Phospho-STING (Ser366) (D8K6H) Rabbit mAb #40818: Confocal IF analysis of THP-1 cells differentiated

WebJul 16, 2024 · STING (#13647), phospho-STING (Ser366, #50907), phospho-STING (Ser365, #72971), TBK1 (#3504), phospho-TBK1 (Ser172, #5483), IRF3 (#4302), phospho-IRF3 (Ser396, #4947) and normal Rabbit... WebAfter TBK1 phosphorylates STING at residue S366, phospho-STING forms a platform at the carboxy-terminal tail (CTT) for recruitment of interferon regulatory factor 3 (IRF3) 14 . IRF3 is then ...

Web(19781) Phospho-STING (Ser366) (D7C3S) Rabbit mAb Sign in or register to save this reagent to your favourites Supplier Cell Signaling Technology Host Rabbit Type Primary … WebProduct Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor ® 647 fluorescent dye and tested in-house for direct flow cytometric and …

WebThe Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 …

WebSTING (phospho-Ser366) rabbit pAb Catalog No : YP1518 Reactivity : Human;Rat;Mouse; Applications : WB Target : STING Protein Name : STING (Ser366) Human Swiss Prot No : Q3TBT3 Immunogen : Synthesized phosho peptide around human STING (Ser366) Specificity : This antibody detects endogenous levels of Human STING (phospho-Ser366) … birrung the secret friend activitiesWebMay 19, 2024 · Load the lysate samples and run a 10% SDS-PAGE gel. Set up a mini gel tank and fill it with 1× running buffer prepared from 10× running buffer. Position the gel inside the tank and load the sample in each well. Run the gel at 200 V until the blue dye front is out. bir ruling on issuance of 2307Web64 sting Primary Antibodies: Thermo Fisher antibodies are validated for applications including western blotting, immunocytochemistry, flow cytometry, and chromatin immunoprecipitation. ... Phospho-STING (Ser366) Polyclonal Antibody. 1 Reference 1 Reference 6 figures. Target . Human Mouse Rat. Details. Rabbit Polyclonal. Application. … dan hayward spokane attorneyWebPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / … birrunga gallery cafeWebAug 27, 2024 · Sections were incubated with CD68 antibody (GB14043, Servicebio) together with anti-Phospho-STING (phosphor Ser366, 85735, Cell Signaling Technology) or anti-Phospho-IRF3 (phosphor Ser396, 29047S ... danh bai online freeWebThe scaffolding function of STING and other adaptors may explain why IRF3 is activated only in a subset of signaling pathways that activate TBK1. ... IRF3 also bound to phospho-TBK1 [TRAF family member-associated NFκB activator (TANK)-binding ... Further, Ser366 and Leu374 of STING, but not Ser358, are required for phosphorylation of IRF3 ... birrus internationalWebPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Antibodies are … birrus britannicus