Rac1-gtp检测

Author: hygl

August undefined, 2024

TīmeklisRac1 is a 21 kDa small GTPase, a member of the Ras super-family and Rho sub-family of GTPases, that upon activation by a guanine nucleotide exchange factor (GEF), is essential in regulating GLUT4 translocation and actin cytoskeletal re-arrangement as a part of a signal transduction pathway transducing extracellular signals (activation of … TīmeklisRac1/2/3 Antibody 可检测内源水平的 Rac1/2/3 总蛋白。该抗体不会与其他小 GTP 酶发生交叉反应。 ... GTP 结合刺激 Rac/Cdc42 蛋白的活性，然而通过蛋白质内部 …

小G蛋白Rac1——肌动蛋白细胞骨架动力学和GLUT4的调节因子

Tīmeklis2024. gada 1. jūn. · 26903-rac1-GTP活性检测抗体. 背景资料：小型GTPas是一个超级系列的蜂窝信号调节器。. Rac 属于 GTPases 的 Rho 子家族，该家族调节细胞活性、细胞分裂和基因转录。. GTP 绑定增加了 Rac 的活性，GTP 对 GDP 的水解使其处于非活动状态。. GTP水解由GTPase激活蛋白质（GAPs ... Tīmeklis结果: 1.实时荧光定量PCR结果显示:与对照组相比,TGFβ_1刺激后RhoA mRNA表达增加,并呈一定的浓度依赖性;而Rac1,Cdc42 mRNA表达无明显变化;各浓度PDGF-BB刺激后大鼠肝星状细胞RhoA,Cdc42,Rac1 mRNA表达无明显差异. 2.Western blot检测结果显示,不同浓度TGFβ1,PDGF-BB对大鼠肝星状细胞 ... greece map and flag

Anti-Active Rac-GTP, monoclonal NewEast Biosciences - Biomol

Tīmeklis本发明属于分子生物领域，一种检测小分子G蛋白Rapl活性的方法及试剂盒。背景技术小分子G蛋白RapI属于Ras家族，其结构类似于Ras，当结合GTP后处于活性状态(Rap1-GTP)，结合GDP后则处于非活性状态(Rap1-⑶P)。在细胞内，RapI通过Rap1-GTP与Rapl-GDP之间的动态转换起分子开关的作用，胞外信号通过特异性鸟嘌呤 ... TīmeklisATP酶和GTP酶分别催化ATP和GTP释放出游离磷酸（P i），BK050，BK051，BK052，BK053和BK054都是通过与报告染料结合或通过酶转化为报告分子来测量释放的磷酸盐以检测酶促反应的过程，BK051，BK052，BK053，BK054均适用于高通量筛选。其中BK053和BK054（ … Tīmeklistranscription, and cell transformation. Like other small GTPases, Rac1 regulates molecular events by cycling between an inactive GDP-bound form and an active GTP-bound form. In its active (GTP-bound) state, Rac1 binds specifically to the p21-binding domain (PBD) of p21-activated protein kinase (PAK) to control downstream signaling … florists mutual insurance edwardsville il

5879 - Gene ResultRAC1 Rac family small GTPase 1 [ (human)]

TīmeklisRac Pull-Down Activation Assay Kit Cat. # 80501 Introduction A. Background Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it … TīmeklisRac1-GTP 单抗货号: 26903 规格: 30 µL 基因符号: RAC1 描述: Anti-Rac1-GTP Monoclonal Antibody 背景介绍: Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the … greece map corinthTīmeklisRab7 Pull-Down Activation Assay Kit Cat. # 82501 Introduction A. Background Small GTPases are a super-family of cellular signaling regulators. The small Ras-like GTPase Rab7 is an evolutionary … florists monroe township nj

"Tīmeklis用于研究领域中研究 Rap1A 的检测试剂盒。 ... Active Rap1 Detection Kit 提供了检测细胞中激活 Rap1 GTP 酶所必需的所有试剂。GST-RalGDS-RBD 融合蛋白用于结合 … " - Rac1-gtp检测

Rac1-gtp检测

Tīmeklis配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。. A synthetic phosphorylated peptide around S71 of human RAC1 (NP_008839.2). Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Tīmeklis2024. gada 10. apr. · The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript …

Did you know?

TīmeklisActive Rac1 Detection Kit 提供了检测细胞中Rac1 GTP 酶活化所必需的所有试剂。GST-PAK1-PBD 融合蛋白用于结合活化形式的 GTP 结合 Rac1，GTP 结合 Rac1 随后可 … Tīmeklis本发明涉及一种取代的吡啶并嘧啶酮类衍生物、其制备方法及含有该衍生物的药物组合物在医药上的应用。具体而言，本发明涉及一种通式(i)所示的取代的吡啶并嘧啶酮类衍生物、其制备方法及其可药用的盐，以及它们作为治疗剂，特别是sos1抑制剂的用途，其中通式(i)中的各取代基的定义与说明书 ...

TīmeklisRap1 活性检测试剂盒 ... 81401 规格: 30 Assays 产品全名: Rap1 Pull-Down Activation Assay Kit 应用: Pull-Down 监测: Active Rap1-GTP level. ... 查看详情. Rac1 小鼠单抗/Anti-Rac1 Mouse Monoclonal Antibody. 型号：26005 ... Tīmeklis1992. gada 1. jūn. · Rac1, a member of the family of low-molecular-mass GTP-binding proteins, functions in phagocytic leukocytes as a component necessary for activation …

TīmeklisRac GTP酶片段的化学式为C46H74N12O14，氨基酸序列为NH2-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH，分子量为1019.15。Rac是GTP酶Rho家族的亚家族，是一种小的信号G蛋白（更具体的GTP酶）。Rac1在各种癌症中的发展中发挥显著作用，包括黑色素瘤(1)和非小细胞肺癌(2)。Rac1是一个小信号G蛋白，更具体地说是GTP酶，分子量约 ... TīmeklisRac1 Activation Assay Kit被设计来鉴定贴壁细胞或非贴壁细胞的细胞裂解液中Rac活性数量 (i.e. Rac-GTP, rather than the inactive Rac-GDP). 使用的glutathione (GST) pull …

Tīmeklis2016. gada 2. jūn. · Rho/ROCK信号通路诱导细胞骨架重组、细胞迁移和应力纤维形成,与内皮通透性、组织收缩和生长等多种生理功能有关,参与糖尿病肾病、眼疾病、肿瘤、心脏病、神经损伤性疾病、高血压、辐射损伤和白血病等疾病的发生,作为药物研发靶点越来越得到人们的关注 ...

Tīmeklis2024. gada 6. apr. · 最近，Wan等在转基因斑马鱼模型发现，足细胞Rac1活性的升高程度与其对足细胞损害程度呈剂量依赖性，中等程度Rac1活性升高并不损害肾小球滤过屏障，但加重甲硝唑会导致足细胞损伤；当Rac1活性显著升高时，nephrin及podocin表达显著下降，导致大量蛋白尿、足突 ... florist smithers bcTīmeklisRac1/Cdc42活化检测试剂盒 The Rac1/Cdc42 Activation Assay provides an effective method for detecting Rac & Cdc42 activity in cell lysates.; find Sigma-Aldrich-17441 MSDS, related peer-reviewed papers, technical … florists natchitoches laTīmeklis2024. gada 18. marts · 摘要目的: 分析肺癌A549细胞Rac1的表达水平及其对细胞吞噬功能的影响。. 方法: 采用姜黄素诱导A549细胞凋亡；采用流式细胞术检测Rac1抑制剂对A549细胞凋亡的影响；将A549细胞与同系凋亡细胞共培养，应用荧光显微镜技术观察Rac1下调对A549细胞清除凋亡细胞能力的 ... florists mt vernon waTīmeklisNewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at … greece mapchartTīmeklis2024. gada 28. janv. · 概述. Active Rac1 GTP [26903] ¥：4800.00. [30 µL] Catalog Number: 26903. Gene Symbol: RAC1. Description: Anti Active Rac1-GTP Mouse Monoclonal Antibody. Background: Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell … greece map englishTīmeklis2024. gada 10. apr. · METH已成为继海一洛因之后的国内第二大成瘾性药物。. 然而，针对METH成瘾机制目前仍未完全阐明，缺乏有效的治疗药物。. 近日，南方医科大学张璐教授课题组在精神病领域顶.级期刊《Biological Psychiatry》上发表题为“Dopamine D1 and D2 Receptors Differentially Regulate Rac1 ... greece map athensTīmeklisZ62954982 (ZINC08010136) is a potent, selective and cell-permeable Rac1 ( IC50 =12 μM) inhibitor that is 4 times more effective than NSC23766 (HY-15723A) ( IC50 =50 μM). Z62954982 disrupts the Rac1/Tiam1 complex and decreases cytoplasmic levels of active Rac1 (GTP-bound Rac1), without affecting the activity of other Rho GTPases … greece map icon