Sphingosine 1-phosphate中文
WebThe bioactive sphingolipid metabolite sphingosine-1-phosphate (S1P) is now recognized as a critical regulator of many physiological and pathophysiological processes, including cancer, atherosclerosis, diabetes and osteoporosis. S1P is produced in cells by two sphingosine kinase isoenzymes, SphK1 and SphK2. Many cells secrete S1P, which can … Web10. apr 2024 · Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates various cellular activities of the immune, cardiovascular and nervous systems [1, 2].In cancer, S1P …
Sphingosine 1-phosphate中文
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WebSphingosine-1-phosphate (S1P) is a biologically active lipid mediator being produced in and affecting macrophages. With central roles of macrophages during inflammation and cancer the sphere of S1P actions touches ground under a number of physiological as well as pathological settings. Web维普期中文期刊服务平台，由维普资讯有限公司出品，通过对国内出版发行的14000余种科技期刊、5600万篇期刊全文进行内容分析和引文分析，为专业用户提供一站式文献服务：全文保障，文献引证关系，文献计量分析；并以期刊产品为主线、其它衍生产品或服务做补充，方便专业用户、机构用户在 ...
WebSphingosin-1-phosphat hat als Signalmolekül vielfältige intra- wie extrazelluläre Funktionen. Besonders hervorzuheben ist seine Bedeutung für: die Zellproliferation: S1P steigert die … Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is also referred to as a bioactive lipid mediator. Sphingolipids at large form a class of lipids characterized by a particular aliphatic aminoalcohol, which is sphingosine. Zobraziť viac S1P is formed from ceramide, which is composed of a sphingosine and a fatty acid. Ceramidase, an enzyme primarily present in plasma membrane, will convert ceramide to sphingosine. sphingosine is then … Zobraziť viac S1P is a blood borne lipid mediator, in particular in association with lipoproteins such as high density lipoprotein (HDL). It is less abundant in tissue fluids. This is referred to as the … Zobraziť viac • Lipid signaling • Lysophosphatidic acid Zobraziť viac • Xie, B.; Shen, J.; Dong, A.; Rashid, A.; Stoller, G.; Campochiaro, P. A. (2009). "Blockade of Sphingosine-1-phosphate Reduces Macrophage Influx and Retinal and Choroidal Neovascularization" Zobraziť viac The levels of S1P (in a range of 5–40 μmol/L) are 5 to 10 times up-regulated in ovarian cancer patients' ascites. S1P at this physiological concentration stimulates migration and invasion of epithelial ovarian cancer cells but inhibits migration of … Zobraziť viac 1. ^ Mendelson, Karen; Evans, Todd; Hla, Timothy (1 January 2014). "Sphingosine 1-phosphate signalling". Development. 141 (1): 5–9. doi:10.1242/dev.094805. ISSN 0950-1991. PMC 3865745. PMID 24346695. 2. ^ Spiegel, Sarah; Milstien, Sheldon (26 January 2007). Zobraziť viac
Webpred 2 dňami · Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-pho... Mechanisms and Biomarkers of Apoptosis in Liver Disease and Fibrosis; Addressing Liver Fibrosis with Liposomes Targeted to Hepatic Stellate Cells; Involvement of Sphingosine 1-Phosphate in Palmitate-Induced Non-Alcoholic Fatty Liver … http://yuxiqbs.cqvip.com/Qikan/Article/Detail?id=37836886
WebIntra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Sphingosine-1-Phosphate (S1P) were tested 20 times on one plate, respectively. Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Sphingosine-1-Phosphate (S1P) were tested on 3 different plates, 8 replicates in ...
WebD-erythro-Sphingosine-1-phosphate(S1P) is a polar sphingolipid metabolite which regulates diverse cellular responses including cell growth, survival and migration. S1P was reported to stimulate DNA synthesis and cell division in quiescent cultures of Swiss 3T3 fibroblasts and to trigger the dual signal transduction pathways of calcium ... grant for elderly home repairsWebComplementary effects of ciclopirox olamine, a prolyl hydroxylase inhibitor and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting. Integr Biol.. 2013-11; SH Lim, C Kim, AR Aref, R Kamm, M Raghunath. grant for electric and gasWebL-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts : Role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation. / Chao, Hung Hsin; Chen, Cheng Hsien; Liu, Ju Chi 等. 於: Journal of Nutritional Biochemistry, 卷 21, 編號 7, 07.2010, p. 580-588. grant for electric billWebSphingosine-1-phosphate is an endogenous second messenger and a ligand for S1PR1. In endothelial cells, S1P (1-20 µM) induced EDG-l-dependent morphogenesis. In HEK293EDG-1 cells, S1P bound to S1PR1 with Kd value of 8.1 nM in a time-dependent way. In cells transfected with EDG-l, S1P activated ERK-1 and ERK-2 via EDG-1. grant for down payment on homeWeb11. apr 2024 · Sphingosine 1-phosphate (S1P) is a pleiotropic lipid mediator involved in various cellular functions such as proliferation, migration, rearrangement of cytoskeleton, adhesion and inflammation in many types of cells, most notably in the immune and vascular systems. Regulation of immune cell trafficking and vascular integrity are two important ... chip as flint in britainWeb12. mar 2009 · The five known members of the sphingosine-1-phosphate (S1P) receptor family exhibit diverse tissue expression profiles and couple to distinct G-protein-mediated signalling pathways. S1P 1, S1P 2, and S1P 3 receptors are all present in the heart, but the ratio of these subtypes differs for various cardiac cells. grant for electric car charger scotlandhttp://html.rhhz.net/ZGYLXTB/html/202408002.htm grant for electric car charger