Temuterkib
WebLY-3214996, also known as Temuterkib, is a potent and selective, orally available inhibitor of extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity. Upon oral administration, LY3214996 inhibits both ERK 1 and 2, thereby preventing the activation of mitogen-activated protein kinase (MAPK)/ERK-mediated signal transduction … WebTemuterkib mesylate C23H31N7O5S2 CID 155907802 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ...
Temuterkib
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WebJan 16, 2024 · Finally, we use ERK KiMBI to screen ERK inhibitors for brain efficacy, identifying temuterkib as a promising brain-active ERK inhibitor, a result not predicted … WebAn official website of the United States government Menu. Search Search
WebTemuterkib. LY3214996. ERK Cancer; Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC 50 of 5 nM for both enzymes in biochemical assays. … WebTemuterkib (LY3214996) is a selective and novel ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. It potently inhibits cellular phospho-RSK1 in BRAF …
WebChemScene Provide Temuterkib(CAS 1951483-29-6)In-stock or Backordered impurities,Bulk custom synthesis,Formular C22H27N7O2S,MW 453.56 bulk manufacturing, sourcing and procurement. WebTemuterkib (LY3214996) is a selective, novel erK1/2 inhibitor with an IC50 of 5 nM against ERK1 and ERK2. It can effectively inhibit intracellular P-RSK1 in cancer cell lines with …
WebApr 23, 2024 · A study involving 335 patients with biliary tract cancers, who underwent next-generation DNA sequencing between October 2024 and April 2024, described two women, of whom, a woman in her 50s [exact age not stated] acquired drug resistance during treatment with zoligratinib, temuterkib and futibatinib for intrahepatic …
Web【编号】：PR1381 【产品名称】：石蚕苷A对照品 【规格】：10mg 【用途】： 石蚕苷A对照品 kitchen counter drain boardWebTEMUTERKIB [INN] TEMUTERKIB [USAN] Resources. Common Chemistry. i. Inxight Drugs. i. NCATS GSRS Full Record. i. NCI Thesaurus. i. PubChem. i. Note. UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings … kitchen counter desk ideashttp://www.fluoroprobe.com/archives/tag/%e7%9f%b3%e8%9a%95 kitchen counter dog food storageWebTemuterkib (LY3214996) Temuterkib (LY3214996) is a selective and novel ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. It potently inhibits cellular phospho-RSK1 in BRAF and RAS mutant cancer cell lines. Pan: ERK1, IC50: 5 nM: S8701: MK-8353 (SCH900353) kitchen counter drain matWebApr 11, 2024 · Live. Bioluminescence helps researchers develop cancer drugs for brain; 2024-04-11 18:35:47 UTC – Magnitude(ML) 2.4 – 1 km W Alfianello (BS) kitchen counter design graniteWebDescription: Temuterkib (formerly LY3214996; LY-3214996) is a selective, ATP-competitive and orally bioavailable inhibitor of the ERK1 (extracellular signal-regulated kinase) and ERK2 with potential anticancer activity. It inhibits ERK1/2 with IC50 value of 5 nM in biochemical assays. LY3214996 demonstrated antitumor activity in BRAF-mutant models with … kitchen counter dish rackWebTemuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC 50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p … kitchen counter dish drying rack